Pdf anhydrous formic acid and acetic anhydride as solvent. Material safety data sheet acetic anhydride lasec sa. Eastmantm acetic anhydride, reagent grade version 2. Created by global safety management, 18435 5161 section 1. Dispose of contentscontainer to an approved waste disposal plant. When undiluted, it is sometimes called glacial acetic acid. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032 phone. Ethanoic acid, vinegar acid, methanecarboxylic acid. If seeking medical attention, provide sds document to physician. Do not eat, drink or smoke when using this product. Acetic anhydride not listed as a carcinogen by acgih, iarc, ntp, or ca prop 65.
Acetic anhydrideprocess, technology, applications, patent. Acetic anhydride is the chemical compound with the formula ch3co2o. This chemical is on the special health hazard substance list. This fact sheet is a summary source of information of all potential and most severe health hazards that may result from. Flammable liquid, toxic by inhalation, harmful ingestion.
Acetic anhydride certified acs, fisher chemical fisher. Seastar chemicals inc msds acetic acid, glacial page 1 of 6 material safety data sheet acetic acid, glacial print date. Identification of the substancemixture and of the responsible company 1. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n. Since acetic anhydride is a relatively nonvolatile liquid, direct venting of the vapor to the atmosphere from a hole in a ruptured vessel does not consitiute a significant hazard downwind. Material safety data sheet acetic anhydride section 1 chemical product and company identification msds name. Identification of the substancemixture and of the company undertaking 1. Contact with liquid or vapor causes severe burns and possible irreversible eye damage. Any existing industrial property rights must be observed. Acetic anhydride is most suited for the conversion of cellulose into cellulose acetate and in the manufacture of aspirin. The hydrolysis of acetic anhydride in the presence of water is an exothermic reaction that produces acetic acid. Nfpa hmis personal protective equipment 2 3 0 healthhazard 3 firehazard 2 reactivity 0.
See brethericks handbook of reactive chemical hazards for details. Vinegar is no less than 4% acetic acid by volume, making acetic acid the main component of vinegar. Specific hazards arising from the substance or mixture maleic acid and maleic anhydride may form, mostly with iron, pyrophoric products, which at increased temperature may selfignite. Anhydrous formic acid and acetic anhydride as solvent or additive in nonaqueous titrations article pdf available in pharmazie 609. Acetic anhydride is a clear liquid with a pungent, penetrating vinegarlike odor. Ghs product acetic acid 90 100% identifier company name chemsupply pty ltd abn 19 008 264 211 38 50 bedford street gillman sa 50 australia address tel. Concentration % ww acetic anhydride 108247 94 100 acetic acid 64197 0 6 section 4. Acetic anhydride safety data sheet according to federal register vol. First aid eye contact immediately flush with large amounts of cool water. Acetic acid safety data sheet according to federal register vol. Attempts at using 12pyridylpiperazine for the derivatization of maleic, phthalic, and trimellitic anhydrides failed, however, because the resulting derivatives of these. Some things are a little wierd about it, like the fact in the acetic anhydride synth they use a small quantity of acetic anhydride as a solvent.
Material safety data sheet msds phosphoric acid, 85%. Manufacture of acetic anhydride, cellulose acetate, vinyl acetate monomer, acetic. Most of the research has focused on low ratios of acetic anhydride to water. Show this safety data sheet to the doctor in attendance. It is widely used as an acetylating agent or in chemical synthesis. However, as one sees in propionic anhydride, such a. It is a colorless liquid that smells strongly of acetic acid, which is formed by its reaction with moisture in the air. Hazardous reaction has not been reported stability materials to avoid possibility of hazardous reactions.
Acetic anhydride safety data sheet according to the federal final rule of hazard communication revised on 2012 hazcom 2012 section 1. Acetic acid anhydride, acetic oxide, acetyl oxide, ethanoic anhydride. Acetic anhydridepyridine ts shelf life on ship date. Acetic acid is on the right to know hazardous substance list because it is cited by osha, acgih, dot, niosh, nfpa and epa. Acetic anhydride, or ethanoic anhydride, is the chemical compound with the formula ch 3 co 2 o. Sds of acetic anhydride, safety data sheets, cas 108247. Chemical product and company identification product name. Flush skin and eyes with copious amounts of water for at least 2030 minutes, holding lids apart to ensure flushing of the entire surface. It is a colorless liquid that smells strongly of acetic acid, which is formed by its reaction with. It acts as a wood preservative and solvent in examination of wood fat, fatty and volatile oils and detection of rosins. Acetic anhydride can be made by passing vaporizing glacial acetic acid and passing it through a small furnace to increase temperature to around 900 deg f. It has been reported to promote the knoevenagel condensation of various aldehydes and activated. Fisher scientific 1 reagent lane fair lawn, nj 07410 for information, call.
Chemical product and company identification page number. Containers of this material may be hazardous when empty since they retain product residues vapors, liquid. September 2011 section 1 chemical product and company identification msds name. Name distributor acetic acid, glacial the science company catalog numbers. First aid measures description of first aid measures.
The largest volume use for acetic anhydride is as a raw material for cellulose acetate fibers and plastics. Keep container tightly closed do not eat, drink or smoke. If ingested, seek medical advice immediately and show the container or the label. Acetyl chloride, acetic anhydride and propionic anhydride. Identification of the substancemixture and of the companyundertaking 1. Commonly abbreviated ac 2 o, it is the simplest isolable anhydride of a carboxylic acid and is widely used as a reagent in organic synthesis. Accidental release measures contain spill and collect, as appropriate. Mixtures name product identifier % ghs us classification water casno. Commonly abbreviated ac2o, it is one of the simplest acid anhydrides and is a widely used reagent in organic synthesis. Material safety data sheet rna biotechnology section 1. A meta description is an html tag in the html code of your website, which allows you to customize a section of text that describes the page itself. The main process involves dehydration of acetic acid to give ketene at 700750 c.
Acetic anhydride is a carboxylic acid anhydride commonly used as an acetylating agent for amines and alcohols. Acetic anhydride reacts violently on contact with water, steam, methanol, ethanol, glycerol and boric acid. It plays a role in how your page is seen by search engine crawlers, and how it appears in serps. Ghs classification in accordance with 29 cfr 1910 osha hcs.
Seastar chemicals inc msds acetic acid, glacial page 2 of 6 section 4 first aid measures eyes. Name of substance maleic anhydride identifiers cas no 108316 molecular formula c4h2o3 molar mass 98. Cas 64197 acetic acid, acs 90 % percentages are by weight section 4. As the vapors pass through the furnace coils a catalyst such as diammonium phosphate dap is injected. Product identifier product name acetic acid 50 80% synonyms, trade names ethanoic acid reach registration number 01211947532830 casno. Acetic acid 64197 99 100% all concentrations are percent by weight unless ingredient is a gas. When released into the soil, this material is expected to leach into groundwater. Prepare a reagent blank all components, solvents, etc. Extremely hazardous in case of skin contact irritant, of eye contact irritant, of ingestion. This chemical laboratory information profile is not a material safety data sheet. Print acetic anhydride certified acs, fisher chemical.
Reaction with water is particularly dangerous in presence with mineral acids e. In rivers, the principal mixing agent is stream turbulence. Acetic anhydride safety data sheet jubilant life sciences. Cdc niosh pocket guide to chemical hazards acetic anhydride. In osha method 82, acetic anhydride is collected on a glass fiber filter impregnated with 12pyridylpiperazine, which reacts with the anhydride to form a derivative. Prolonged skin contact may be painless with reddening of the skin followed be a. Safety data sheet northwest missouri state university. Page 4 of 8 msds acetic acid sparking type tools and equipment, including explosion proof ventil ation. In many organic reactions it acts as a dehydrating agent.
International acetyl company safety data sheet according to regulation ec no. User is solely responsible for investigating and checking the regulatory approval status. Safety data sheet according to 29cfr19101200 and ghs rev. Ketene is thereafter reacted with acetic acid to obtain the anhydride. If inhaled if breathed in, move person into fresh air.
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